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Micro and Nano Systems Letters
Fig. 4 | Micro and Nano Systems Letters

Fig. 4

From: Single to three nucleotide polymorphisms assay of miRNA-21 using DNA capped gold nanoparticle-electrostatic force microscopy system

Fig. 4

a–d Electrostatic force measurements and Gaussian distribution of the DCNPs: a pDNA + c_RNA, b pDNA + M1_RNA, c pDNA + M3_RNA, and d pDNA + NC_RNA. To confirm whether our approach can discriminate between two neighboring conditions (i.e., pDNA + c_RNA/pDNA + M1_RNA, pDNA + M1_RNA/pDNA + M3_RNA, and pDNA + M3_RNA/pDNA + NC_RNA), t-tests were performed to compare the results between each group. P-values were calculated using a t-test (P < 0.05)

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