Fig. 7
From: Methods to isolate extracellular vesicles for diagnosis
Microfluidic system to isolate EVs. Microfluidics techniques developed for EV purification are classified into immunoaffinity approach, sieving EVs, and trapping EVs with porous structures. a Capture of EVs occurs by binding to specific antibodies on channels. The device with antibody increases EV-capture efficiency. b Microfluidics with filter pore size ~500 nm isolate EVs without aggregation. EVs have negatively charged phospholipid membranes and therefore move across filter membranes