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Fig. 7 | Micro and Nano Systems Letters

Fig. 7

From: Methods to isolate extracellular vesicles for diagnosis

Fig. 7

Microfluidic system to isolate EVs. Microfluidics techniques developed for EV purification are classified into immunoaffinity approach, sieving EVs, and trapping EVs with porous structures. a Capture of EVs occurs by binding to specific antibodies on channels. The device with antibody increases EV-capture efficiency. b Microfluidics with filter pore size ~500 nm isolate EVs without aggregation. EVs have negatively charged phospholipid membranes and therefore move across filter membranes

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