Fig. 5
From: Methods to isolate extracellular vesicles for diagnosis
Size-exclusion with (a) filter and (b) chromatography. Sorting targeted-sized EVs by size exclusion. a Filter-based isolation method considers pore size for isolation desired size vesicles. Filter-based isolation requires sorting proteins and EVs. The device with electrophoretic migration processes and size exclusion isolates EVs. b Chromatography with ultracentrifugation for isolation EVs. Small particles enter the pore and move slowly, whereas large particles pass through the column rapidly. EV-containing solution is collected